Just some of the benefits of kefir and in this last post I’ve written about some of the most exciting developments that you likely won’t find anywhere else and that mostly has to do with increasing the anti-oxidant potential of kefir with co-fermenting additions for the treatment of diabetes. The results are astounding and significant.

Buttermilk (the US version of kefir) has very high anti-oxidant capacity and is rated as one of the highest anti oxidants out there.

For your convenience, from The Breakfast Club mostly because it’s educational regarding weight gain and insulin.


My review of the no sulfate shampoos and conditioner. Unless you plan on sweeping the floor with your hair, don’t bother. Leaves hair feeling unwashed, un-rinsed, dull, lifeless and feeling extremely dry and straw like. Not a good investment. The shampoo will be used as a hand wash. The conditioner will likely be trashed. I noticed no difference in hair loss. My recommend, iodine or B vitamins.

I was remiss, in addition to empathy with my friend on the health issues occurring for your Mom who is 95, my condolences also to my friend on the loss of your Dad.

Benefits Of Kefir For Diabetes

Fermentation of a milk matrix produces kefir. 

Regular consumption of kefir has been associated to the reduction of severity of inflammatory bowel disease, antihypertensive effect, anticarcinogenic effect, increased insulin sensitivity, improved lipid profile, therapeutic effects on osteoporosis, and neurodegenerative disease. The positive health effects have been related to the antioxidant capacity and modulation of the intestinal microbiota by the kefir drink.

Since the 6th millennium BC, milk has featured in the human diet. In order to increase its shelf life, surplus milk was fermented. Early humans discovered that preserved sour milk maintain their nutrients and is relatively more stable. Kefir is a homemade dairy beverage generated through fermentation of lactose in milk by bacteria and yeasts naturally existent in kefir grains. Traditionally, the fermentation of kefir was performed for 24 h at room temperature in goatskins, clay pots, or wooden buckets. The ruminants’ (cows, goats, sheep, camels, or buffalo) milk was applied as the fermentation substrate, in which at the end of this procedure kefir was isolated from the grains by drawing the beverage off.

Kefir can be produced either via the traditional method or a commercial process. The small-scale production calls for direct addition of kefir grains to milk that has been pasteurized and cooled to 20–25 °C.

When producing at a large scale, kefir can be manufactured by using commercial starter cultures that are directly inoculated into the milk or by using the “Russian method”. This involves a backslopping procedure, a serial fermentation processes that begins with kefir produced from grains that are then used as natural starter cultures for milk fermentation. Although kefir can be produced from different sources of animal milk, kefir made from cow’s milk remains the most popular in Eastern Europe. Nevertheless, similar to other fermented milk products the condition of raw milk is crucial for kefir production. By and large, the raw milk for manufacturing kefir should be: rich inconstituent, low bacterial and somatic cell counts, and lack of pathogens or hindering substances, like antibiotics and disinfectant remains.

Effect on Plasma Glucose

Diabetes mellitus is a chronic glucose metabolism disorder with severe clinical consequences, such as retinopathy, nephropathy, and stroke. Type 2 diabetes mellitus is a metabolic disorder marked by the rise in blood glucose due to a decrease in insulin secretion by pancreatic β-cells and insulin resistance. Additionally, the increase in the prevalence of diabetes mellitus worldwide in recent decades is associated with the rise in the prevalence of obesity in the population.

A state of high blood glucose concentration or hyperglycemia, occurring from inadequacies in insulin secretion, action, or both is a complex chronic condition that positions patients at high risk for long-term macro- and microvascular complications. According to the International Diabetes Federation (IDF), 1 in 11 adults (20–79 years) has diabetes (463 million people), which make it a global pandemic. Without suitable treatment, persistent hyperglycemia may cause glucose toxicity, which may gradually damage the secretion of insulin. The requirement of absurdly high-cost insulin therapy is significant to reversing the toxic effect of high blood glucose levels on the pancreas. However, in the last decade, growing evidence has shown the anti-diabetic effects of kefir as a potential low-cost therapeutic drug.

A clinical trial in 60 diabetic patients aged from 35 to 65 years showed that kefir decreased the fasting blood glucose and HbA1C levels  

Earlier anti-diabetic effects of kefir can be observed in a study accomplished by Teruya et al. in which they found fractions of kefram-kefir were effective in the management of Type II diabetes by activating PI 3-kinase or other upstream molecules in the insulin signaling pathway, which resulted in the augmentation of glucose uptake. Later research on genetically diabetic mice fed kefiran for 30 days demonstrated a strong tendency for blood glucose levels to decrease as compared to the control group where the blood glucose concentrations increased continuously during the experiment. In another study, Kwon et al. showed that inhibition of hydrolytic enzymes called α-glucosidases and the pancreatic α-amylase can significantly decrease the postprandial increase of blood glucose levels after a mixed carbohydrate diet and, therefore, can be an important strategy in the management of type-II diabetes. By using this strategy, Kwon et al. demonstrated that α-glucosidase inhibitory activity had increased moderately in kefir culture-mediated fermented soy milk supplemented with Rhodiola extracts exhibiting a better anti-diabetic functionality. A recent study also proved the capacity of kefir fermented soy milk (FSM) as manifested by inhibition of α-amylase activities. They also found that the administration of FSM to hyper-caloric high-fat-high-fructose diet (HFFD) rats inhibited intestinal and pancreas α-amylase activity by 26 and 31% as compared to untreated HFFD-rats, and consequently decreased the blood glucose by 36%. Hadisaputro et al. studied the effects of plain kefir oral supplementation on the hyperglycemia of Wistar rats induced by streptozotocin for 30 days and revealed that kefir consumption was able to lower plasma glucose compared with the control group. Similar results were attained by Alsayadi et al. who found that administration of kefir on streptozotocin-induced diabetic Wistar rats for 35 days showed lowered blood glucose levels in diabetic rats groups which were given water kefir instead of drinking water. Another study also supported the ability of kefir to the lower blood glucose level in STZ-diabetic rats to a significant level. Different milk sources that were used for kefir fermentation also affect the anti-diabetic activity of kefir. The results obtained by Nurliyani et al. on the anti-diabetic potential of kefir combination from goat milk and soy milk in rats induced with streptozotocin-nicotinamide, demonstrated that diabetic rats fed with the kefir combination had lower plasma glucose than rats fed with goat milk or soy milk kefir alone. A clinical trial on the effect of kefir on glucose and lipid profile control in 60 diabetic patients aged from 35 to 65 years which was conducted by Ostadrahimi et al. showed that kefir decreased the fasting blood glucose and HbA1C levels and can be useful as a complementary or adjuvant therapy for the prevention of diabetes. Administration of kefir daily intake with metformin among the newly diagnosed type-2 diabetic adult male patients in the Gaza Government, has shown significant differences in some blood biochemical parameters. The results demonstrated a decrease in fasting blood sugar (FBS), glyco-hemoglobin (HbA1c), and phosphorus with an increase in calcium among diabetic adult males upon kefir intervention. Furthermore, a study on the total incremental plasma glucose area under the curve (iAUC) for strawberry kefir, orange kefir, and low-fat plain kefir showed kefir as a low-to moderate-glycemic index (GI) food, which indicated its suitability for individuals with diabetes.

Bioactive compounds in kefir were tested on glucose metabolism in obesity and diabetes murine models in vivo. Oral administration of a mixture of EPS-producer (exopolysaccarides) Leuconostoc mesenteroides and Lactobacillus kefiri during eight weeks did not affect the plasma glucose level but treatment effectively reduced adipocyte tissue weight by 36%, in addition to downregulating the proinflammatory and fatty acid synthesis gene expression in the adipocytes. This indicates that the regulation of fatty acid metabolism in adipose tissue is not a determining factor in promoting a significant change in plasma glucose.

In contrast, administration of a mixture of 5 to 20 mL of kefir with black rice extract—1 : 1/kg bw—during four weeks enhanced by up to 199% and 2330% of the Langerhans islet in the pancreas and insulin-positive β-cells, respectively, in diabetic rats. The concentration completely reversed the pancreatic damage induced by STZ-NA (Streptozotocin-nicotinamide), achieving a similar effect to the glibenclamide, an antidiabetic drug of the second-generation sulfonylureas class that reduces blood glucose by increasing insulin secretion from pancreatic β-cells. The effect was attributed to the proton-radical scavenging activity from alcohol and phenolic compounds present in the beverage. This finding demonstrates that the antioxidative capacity must be a significant factor in promoting the homeostasis of insulin production by the pancreas. The study did not test a formulation without adding black rice extract therefore it is impossible to determine how much of this positive effect on β-cells can be attributed to the kefir alone. Indeed, the addition of black rice extract increased by 56.8% the antioxidant capacity of the beverage compared to the kefir alone.

The effect of bioactive compounds of kefir on glucose metabolism are inconclusive, so further studies with pure kefir drink or with bioactive compounds isolated from it are urgently needed.

Kefir Benefits For Diabetes

  • Alleviates pro inflammatory assault  
  • Fat loss
  • Reverse pancreatic damage
  • With the addition of black rice extract, enhances Langerhans islet in the pancreas by approx. 200% and insulin-positive β-cells over 2000%
  • Decrease fasting blood glucose and HbA1C
  • Significantly and continuously lowers blood glucose

In essence…

The natural precursor of ‘gut and immune disorders’ is a dysfunctional autophagic or phagocytic system associated with SAM (severe acute malnutrition) resulting in hundreds if not thousands of chronic ‘conditions’ that worsen over time. See about page for more info and some short lists of these chronic conditions (can eventually impact any and all bodily systems). In the elderly or immune compromised this can occur as ‘senescence’ of the immune system or ‘tolerance’ (an altered immune response, usually over inflammatory). This condition can begin at birth. The immune system includes the ability to detox. The ’cause’ of these conditions is not diet. They can begin or be made worse by acquired immune deficiency syndromes. Natural oral immune therapy ‘resets’ the gut as close to nature as possible as it occurs at birth and helps restore nutrition, tolerance and homeostasis as well as providing anti oxidant protection.

Colostrum and other friendly organisms provide signals to the immune system by inducing tolerance to food and noninvasive antigens, thus avoiding the onset of an abnormal immune response while promoting its maturation and an adequate immune response against pathogens at the same time.
In the absence of A, B, or C (see hierarchy of risk factors in alternavita critical info) it must be D, follow the known intoxicant.

Alternavita: All you need to know (critical info in a nutshell)..... by focusing exclusively on these foundational health and immune development issues up to 90% of chronic conditions can be eliminated.

WHO STATEMENTS: 2017 Millennium Goal

  1. Breastfeeding,
  2. food (security)
  3. and water security (sanitation)

are major protective factors against malnutrition and critical factors in the maturation of healthy gut microbiota, characterized by a transient bifidobacterial bloom before a global rise in anaerobes. Early depletion in gut Bifidobacterium longum, a typical maternal probiotic, known to inhibit pathogens, represents the first step in gut microbiota alteration associated with severe acute malnutrition (SAM). Later, the absence of the Healthy Mature Anaerobic Gut Microbiota (HMAGM) leads to deficient energy harvest, vitamin biosynthesis and immune protection, and is associated with diarrhea, malabsorption and systemic invasion by microbial pathogens. A therapeutic diet and infection treatment may be unable to restore bifidobacteria and HMAGM.


Researchers found that malnourished children’s microbiota failed to follow the healthy pattern they identified in healthy children. The microbiota of malnourished children is immature, lagging in development behind that of their healthy peers. Supplementing these children’s meals with widely used therapeutic foods that increase calories and nutrient density reduces deaths from malnutrition, but it does not fix their persistent microbiota immaturity.

“Perhaps more insidious than slowing growth is malnutrition’s effect on less visible aspects of health, including impaired brain development and dysfunctional immunity, which follow these children throughout their lives”.

The Father of The Microbiome

Dr. Jeffrey Gordon


SIBO can cause severe malabsorption, serious malnutrition and immune deficiency syndromes in children (non breastfed) and adults. 

Prognosis is usually serious, determined mostly by the underlying disease that led to SIBO.



The WHO recommends that immunization or treatment be orally administered due to economic, logistical and security reasons. Furthermore, this route offers important advantages over systemic administration, such as reducing side effects, as the molecules are administered locally and have the ability to stimulate the GALT immune responses  (Levine and Dougan, 1998Neutra and Kozlowski, 2006Bermúdez-Humarán et al., 2011).



For ANY infectious or parasitic disease to start, it is ALWAYS a requisite that the host suffer IMMUNODEFICIENCY. At the same time, infectious and parasitic diseases themselves cause additional IMMUNE SUPPRESSION and more MALNUTRITION. This immune suppression is SECONDARY to the accumulation of free radicals, especially oxidizing species, that occurs during and after infectious and parasitic diseases.

Clinical Aspects of Immunology and Biochem J.


Current IBD Research 2016

Currently available treatments for IBD, which target the systemic immune system, induce immunosuppression, thereby exposing the patient to the risk of infections and malignancy. The interplay between the gut and the systemic immune system determines the final effect on target organs, including the bowel mucosa. Inflammatory bowel diseases (IBD) are associated with an altered systemic immune response leading to inflammation-mediated damage to the gut and other organs.

Clinical & Translational Immunology (2016)
Gastroenterology and Liver Units, Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel

Most importantly, the immune modulatory agents used today for IBD do not achieve remission in many patients.

Not all IBD patients benefit from currently available drugs. Young people with IBD do not want to be on long-term drug therapy. Oral immune therapy, while not yet studied in large cohorts of patients, may provide an answer to this unmet need.

Clinical & Translational Immunology (2016)
Gastroenterology and Liver Units, Department of Medicine, Hebrew University-Hadassah Medical Center, Jerusalem, Israel


Tolerance is the ability of the immune system to ‘see’ and respond appropriately. Without galactose (a necessary sugar) the immune system can not 'see'. Your immune system would not be able to function without galactose Your body wouldn’t know which cells are “good” and what cells are “bad.” Your body wouldn’t know who the invaders were and which ones should be attacked by antibodies. As you will learn the importance of these ‘sugars’ in gut microbiota health is a rapidly expanding field of research, only recently discovered, including HMO's (human milk oligosaccharides).

Why galactose? Milk sugar aka lactose has been shown to be very beneficial for the human body though unlike sucrose, lactose is made up of glucose and galactose. There is no fructose in lactose. It is a healthy disaccharide sugar. Galactose is known as the “brain sugar” and supports brain development of babies and children. Galactose helps triggers long-term memory formation. Galactose has been shown to inhibit tumor growth and stop its spread, particularly to the liver. This beneficial sugar can also enhance wound healing, decrease inflammation, enhances cellular communication, and increases calcium absorption.
What does immune ‘tolerance’ mean in simple language?
Immune tolerance, or immunological tolerance, or immunotolerance, is a state of unresponsiveness of the immune system to substances or tissue that have the capacity to elicit an immune response in a given organism. The Th1 cytokine profile is vital for clearance of certain organisms and ancillary immune activity, and a limiting effect on this cytokine profile may result in reduced chances for overcoming infections especially intra-cellular organisms residing within macrophages. Effective clearance will depend on appropriate macrophage activation (which occurs through IFN≥ release by Th1 and NK cells) and production of nitric oxide. If this pathway is disrupted IFN≥ secretion is blocked, impairing macrophage activation. Persistent blockade of these inhibitory receptors has lead to the breakdown in immune self tolerance, thereby increasing susceptibility to autoimmune or auto-inflammatory side effects, including rash, colitis, hepatitis and endocrinopathies. Many drugs may cause checkpoint blockade toxicity including pharmaceutical drugs termed ‘immuno therapy’ by pharmaceutical companies, these include Mab drugs and cancer treatments. Checkpoint Inhibitor–Induced Colitis: A New Type of Inflammatory Bowel Disease? Madeline Bertha, MD MS, corresponding author1 Emanuelle Bellaguara, MD, Timothy Kuzel, MD, and Stephen Hanauer, MD ACG Case Rep J. 2017; 4: e112. Published online 2017 Oct 11. doi: 10.14309/crj.2017.112 PMCID: PMC5636906 PMID: 29043290

The Elderly

Mammal milk is required for enhanced phagocytosis as shown by research, especially in the elderly. Whole fat mammal milk can actually restore phagocytosis in senescent cells in the elderly. Phagocytosis, by which immune cells ‘eat’ bacteria or infected cells, is one of the mechanisms that help to resist infections. Lactic acid bacteria strains like acidophilus also increases phagocytosis.