The library is for those readers who wish to view original scientific sources as featured in Alternavita Magazine©.

Alternavita Magazine© Feature Article September 2018



Beyond Nutrition

1. Mechanisms of Action of Kefir in Chronic Cardiovascular and Metabolic Diseases.

2. The Role of Probiotics in Cancer Treatment: Emphasis on their In Vivo and In Vitro Antimetastatic Effects

3 Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes

4. Selective induction of apoptosis in human gastric cancer cells by Lactobacillus kefiri (PFT), a novel kefir product

5. Kefir peptides prevent high-fructose corn syrupinduced non-alcoholic fatty liver disease in a murine model by modulation of inflammation and the JAK2 signaling pathway.

6. Deleterious Metabolic Effects of High Fructose Intake: The Preventive Effect of Lactobacillus kefiri Administration.

7. Kefir Supplementation Modifies Gut Microbiota Composition, Reduces Physical Fatigue, and Improves Exercise Performance in Mice.

8. The Microbiota and Health Promoting Characteristics of the Fermented Beverage Kefir

Alternavita Magazine© Feature Article August 2018



The Champagne Of Milk

Why is kefir gaining clinical popularity as an emerging nutra-ceutical? The interest in developing functional foods is increasing because people want to improve their health and prevent diseases. Kefir is a mildly acidic fermented beverage with high probiotic activity, produced by the addition of lactic acid bacteria and yeasts to milk. The composition of kefir varies according to factors such as milk type and the microbiological composition of culture types; kefir grain or commercial starter culture. The microorganisms in kefir produce vitamins, degrade protein and hydrolyse lactose, resulting in a highly nutritious and digestible functional food.

1. A review: chemical, microbiological and nutritional characteristics of kefir: CyTA – Journal of Food: Vol 13, No 3
2. Lactic Acid Bacteria and Bifidobacteria with Potential to Design Natural Biofunctional Health-Promoting Dairy Foods
3 Milk kefir: composition, microbial cultures, biological activities, and related products
4. Fruits and vegetables, as a source of nutritional compounds and phytochemicals: Changes in bioactive compounds during lactic fermentation
5. Kefir peptides prevent high-fructose corn syrup-induced non-alcoholic fatty liver disease in a murine model by modulation of inflammation and the JAK2 signaling pathway.

Alternavita Magazine© Feature Article July 2018

Whey To Go For Protein Power

Combatting Protein Energy Malnutrition With Liquid Whey

What is Protein Energy Malnutrition/Protein Calorie Malnutrition?

Protein energy malnutrition (PEM) is defined as a form of malnutrition due to lack of protein and can be moderate to severe

Types of protein malnutrition are:

Kwashiorkor: Protein malnutrition dominant
Marasmus: Deficiency in calorie intake
Marasmic Kwashiorkor: Marked protein deficiency and marked calorie insufficiency, the most severe form (PCM)

Protein energy malnutrition can have significant lifelong effects



Whey To Go For Protein Power

1. Review
Therapeutic Potential of Milk Whey
2. Acid whey: Is the waste product an untapped goldmine?
3. Initiation of a cure for kwashiorkor patients using a whey milk product. A comparison with cows milk
4. Growth and Nutritional Biomarkers of Preterm Infants Fed a New Powdered Human Milk Fortifier: A Randomized Trial
5. Whey protein hydrolysate and branched-chain amino acids downregulate inflammation-related genes in vascular endothelial cells
6. Goat whey ameliorates intestinal inflammation on acetic acid-induced colitis in rats

Alternavita Magazine© Feature Article June 2018

The Living Immune System

Why is mammal milk a biologically active life giving force for immunity?

Colostrum is such an important part of mammalian evolution that most mammals literally cannot
survive without it and today’s research is indicating that the human mammal may be no different The foundation for the optimal health of each new born mammal begins with colostrum and ends with an optimal period that differs across species of later lactation milk before proper weaning for the
lifelong benefit of the mammal.



The Living Immune System

1. Beneficial Microorganisms in Medical and Health Applications

2. Copyright (C) 2013 by the American Society for Nutrition autism, allergy, and HIV, the microbiota and general gut integrity play a role.
3 Digested artificial baby milk, but not breast milk, kills normal cells
4. 2015 Cultivating healthy growth and nutrition through the gut microbiota
5. kwashiorkor microbiome causal factor
6. The Science of Mother’s Milk-1
7. A molecular basis for bifidobacterial enrichment in the infant gastrointestinal tract…..Expression studies indicate that many of these key functions are only induced during growth on milk oligosaccharides and not expressed during growth on other prebiotics. (Garrido D., 2012)

8. Polyvalent immunoglobulins (a bovine colostrum concentrate) in the treatment of Sjogren’s syndrome in a vegetarian with stomatitis, glossodynia, xer… – PubMed – NCBI

More sources not included in Alternavita Monthly Magazine© June 2018


Kwashiorkor is a form of acute malnutrition, and it seems to be caused by environmental factors and a lack of protein in the diet. Recently, the team of Prof. Gordon at WUSTL established that the microbiome is one of the causal factors in this disease. This is one of the few cases in which we have advanced enough to have established a “bad microbiome” to be one of the causal factors of a disease. Granted, it is not the only factor, but it is one of them rather than just a marker of the disease. NIH’s medline on Kwashiorkor Smith et al., 2014, Gut microbiome of Malawian twin pairs discordant for kwashiorkor.

Abstract: Kwashiorkor, an enigmatic form of severe acute malnutrition, is the consequence of inadequate nutrient intake plus additional environmental insults. To investigate the role of the gut microbiome, we studied 317 Malawian twin pairs during the first 3 years of life. During this time, half of the twin pairs remained well nourished, whereas 43% became discordant, and 7% manifested concordance for acute malnutrition. Both children in twin pairs discordant for kwashiorkor were treated with a peanut-based, ready-to-use therapeutic food (RUTF). Time-series metagenomic studies revealed that RUTF produced a transient maturation of metabolic functions in kwashiorkor gut microbiomes that regressed when administration of RUTF was stopped. Previously frozen fecal communities from several discordant pairs were each transplanted into gnotobiotic mice. The combination of Malawian diet and kwashiorkor microbiome produced marked weight loss in recipient mice, accompanied by perturbations in amino acid, carbohydrate, and intermediary metabolism that were only transiently ameliorated with RUTF.