Has COVID19 or SARS Ever Met Postulate Requirements?

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It is not too often that you see a patent application filed for treatment before a disease is even identified but that is exactly what appears to be happening with CV19.

On January 21 2020, the Wuhan Institute of Virology applied for a Chinese “use patent” on remdesivir, for the novel use of treating COVID-19.

  1.  Barmann, Jay. “Bay Area-Based Gilead Sees Potential Legal Conflict With China Over Its Coronavirus Drug”. SFist. Impress Media. Archived from the original on March 26, 2020. Retrieved March 22, 2020.

Where have we seen this playbook before?

AIDS and Lyme, which to date seem to indicate striking those with the same high risk factors of CV19 namely:

  • elderly
  • immune suppressed

Has SARS or CV19 ever met postulate requirements?

history:

1957-1958 Pandemic (H2N2 virus)

In February 1957, a new influenza A (H2N2) virus emerged in East Asia, triggering a pandemic (“Asian Flu”). This H2N2 virus was comprised of three different genes from an H2N2 virus that originated from an avian influenza A virus, including the H2 hemagglutinin and the N2 neuraminidase genes. It was first reported in Singapore in February 1957, Hong Kong in April 1957, and in coastal cities in the United States in summer 1957. The estimated number of deaths was 1.1 million worldwide and 116,000 in the United States..

Pandemic years were difficult to distinguish from nonpandemic seasons, even in terms of peak monthly mortality. For example, in March of the 1975–1976 nonpandemic season (the season prior to the swine flu scare), the recorded influenza death rate was 22.1 per 100 000 population, nearly as high as the 1968–1969 pandemic peak of 23.3 per 100 000 in January 1969. Likewise, the influenza monthly mortality rate reached 21.9 per 100 000 in February 1960 (a nonpandemic year), surpassing the peak mortality rate of the 1957–1958 pandemic (18.8 per 100 000) 2 years earlier.

Historical influenza mortality data contain many relevant implications for influenza vaccination campaigns. The overall decline in influenza-attributed mortality over the 20th century cannot be the result of influenza vaccination, because vaccination did not become available until the 1940s and was not widely used until the late 1980s.19 This rapid decline, which commenced around the end of World War II, points to the possibility that social changes led to a change in the ecology of influenza viruses.

I found that declining mortality rates occurred simultaneously with expanded influenza vaccine coverage since 1980, especially for the elderly (65 years and older). However, recent research suggests that vaccination is an unlikely explanation of mortality trends. A 2005 US National Institutes of Health study of over 30 influenza seasons “could not correlate increasing vaccination coverage after 1980 with declining mortality rates in any age group.” Other research has reviewed available international studies of inactivated influenza vaccine effectiveness and efficacy. One study concluded that “evidence from systematic reviews shows that inactivated vaccines have little or no effect on the effects measured.” 

Considered in light of the data presented here, these studies imply that other causes–such as an improvement in living conditions or naturally acquired immunity from similar strains of influenza virus–may have been partially responsible for the declining trends in recorded influenza mortality.

 

According to the CDC 11,000 people in US have died exclusively from CV19

About 1 million adults in the US seek care in a hospital due to pneumonia every year, and 50,000 die from this disease….

Remember PCR is not a valid test method for infectious disease according to the inventor of PCR, Kary Mullis. The mere presence of a virus or viral particles is also not valid. According to postulates you must show that the infectious agent causes the disease.

High risk patients:

High risk deaths include those patients who have taken drugs as prescribed.

Drug-related codes associated with the largest percentage increases in deaths between 1999 and 2003 included poisoning due to methadone (275%); poisoning by other and unspecified antidepressants (primarily selective serotonin reuptake inhibitors) [130%]; and poisoning by psychostimulants with potential for abuse (amfetamines and drugs for attention deficit hyperactivity disorder) [117%]. Anticoagulants were associated with the largest numbers of deaths with codes involving “adverse effects in therapeutic use”. Among diseases with significant drug-related aetiologies, Clostridium difficile enterocolitis (associated primarily with antibacterials) had the largest percentage increase in total mentions, with a 203% rise between 1999 and 2003. -“Trends in hospital deaths among human immunodeficiency virus–infected patients during the antiretroviral therapy era, 1995 to 2011” -Journal of Hospital Medicine Volume 10, Issue 9, pages 608–614, September 2015-
(“CONCLUSIONS: Non-AIDS deaths increased significantly during the ART era and are now the most common cause of in-hospital deaths”….. 

Risk factors:

The exact mechanism of how the SARS virus produces damage at cells, tissue, and organs to clinical levels remains elusive. Similar to other viruses such as influenza A virus, Nipah virus, or Ebola virus, SARS-CoV must possess the ability to evade the innate antiviral response of the cells in order to replicate efficiently in the host. 

Tolerance is the ability of the immune system to ‘see’

What does immune ‘tolerance’ mean in simple language?

Immune tolerance, or immunological tolerance, or immunotolerance, is a state of unresponsiveness of the immune system to substances or tissue that have the capacity to elicit an immune response in a given organism.

Most disorders have their root cause in poor gut health, malnutrition and underlying immune deficiency as clearly stated by WHO in 2017 risk factor hierarchal values, which are:

• not breast feeding (chronic immature micro biome not rescued by diet)

• food

• water quality

Breastfeeding, food and water security are major protective factors against malnutrition and critical factors in the maturation of healthy gut microbiota, characterized by a transient bifidobacterial bloom before a global rise in anaerobes. Early depletion in gut Bifidobacterium longum, a typical maternal probiotic, known to inhibit pathogens, represents the first step in gut microbiota alteration associated with severe acute malnutrition (SAM). Later, the absence of the Healthy Mature Anaerobic Gut Microbiota (HMAGM) leads to deficient energy harvest, vitamin biosynthesis and immune protection, and is associated with diarrhea, malabsorption and systemic invasion by microbial pathogens. A therapeutic diet and infection treatment may be unable to restore bifidobacteria and HMAGM. Besides re-feeding and antibiotics, future trials including non-toxic missing microbes and nutrients necessary to restore bifidobacteria and HMAGM, including prebiotics and antioxidants, are warranted in children with severe or refractory disease.

For any infectious or parasitic disease to start, it is always a requisite that the host suffer IMMUNODEFICIENCY. At the same time, infectious and parasitic diseases themselves cause additional IMMUNE SUPPRESSION and more MALNUTRITION. This immune suppression is SECONDARY to the accumulation of free radicals, especially oxidizing species, that occurs during and after infectious and parasitic diseases.

Clinical Aspects of Immunology and Biochem J.